Sequal vascular and biliary complication recurrence and similar numbers of intraoperative RBC transfusion unit

Moreover, the BMI in the Asian population is much lower than the western population. Few investigations discuss the difference of intraoperative blood loss and the needed number of RBC transfusion units of patients with benign liver diseases undergoing LDLT or DDLT. Patients who underwent LDLT had significantly higher intraoperative blood loss than those undergoing DDLT. This difference may be due to the additional transection and the longer surgical duration of the LDLT procedure. However, due to the utility of autologous blood transfusions for patients with benign liver diseases, the total allogenic RBC transfusion was similar between the two groups. In Frasco et al.’s study, LDLT recipients received fewer units of RBC transfusions compared to DDLT recipients. We suggest this difference may be related to the lower MELD score in the living donor transplant patients. Functional recovery is an important part of liver transplantation. Compared with DDLT, patients undergoing LDLT have similar recovery of their liver and renal functions. However, the coagulation function of patients who underwent LDLT was worse during the early postoperative days than of patients who underwent DDLT. More intraoperative blood loss and longer surgical durations may be potential explanations for this finding. Nevertheless, similar liver and renal function recovery between the two groups may be the reason behind the similar postoperative complication incidence and similar long-term survival rates. The long-term survival rates of patients undergoing LDLT versus DDLT were similar in our study. However, Thuluvath et al. suggested LDLT may achieve similar short-term outcomes compared with DDLT. However, the graft survival rate was significantly lower in patients undergoing LDLT. Kashyap et al. reported a higher recurrence rate of primary sclerosing cholangitis in patients undergoing LDLT. This difference may be due to the difference of aetiology of the disease. The advantage of LDLT is the SAR131675 reduced CIT and better donor-recipient compatibility. These advantages may positively affect the long-term survival of LDLT. Moreover, Austin et al. also reports the long-term survival rate in the paediatric population is better with LDLT than DDLT. Emergency liver transplantation is a life-saving treatment for extremely sick patients. However, different countries or centres have different criteria for emergency liver transplantation. In our country, different provinces have different criteria. Consistent with previous studies, the long-term survival rate of patients undergoing emergency liver transplantation was lower than of patients undergoing elective transplantation. The outcomes of patients undergoing emergency LDLT and undergoing emergency DDLT were similar. This result may suggest that for sicker patients, LDLT may achieve similar outcomes to DDLT.

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