Mangrove tannins from C. tagal leaves were successfully characterized by 13C-NMR, MALDI-TOF MS, HPLC-ESI MS and column chromatographic fractionation. They had substantial DPPH free radical scavenging ability and ferric reducing antioxidant power, which could be used as a new source of antioxidants. The major challenge in the research on condensed tannins is probably the difficulty in obtaining them in an individual molecular form. The complete purification of a procyanidin with a DP above five is almost impossible. Therefore, for studying their structures and properties, more or less mixtures polymerized are often employed. More, the synergistic effects of active mixtures make plant extracts and fractions more interesting than the pure compounds for functional food applications. In the present study, an effective fractionation method was established to elucidate more about the relationships between DP and antioxidant activities. The established relationships could be used as a Afatinib side effects theoretical method for predicting the structure-activity of proanthocyanidins. Inflammatory bowel diseases are common gastroenterological disorders among both the paediatric and adult populations. This group of diseases is featured by a chronic, relapsing or remitting course of GI complaints such as diarrhea, rectal bleeding and abdominal cramping, which can result in malnutrition, weakness, electrolyte imbalances, and delayed growth, especially in children. Histopathlogically, inflammation, cell degeneration, ulceration and fistulation may be found in the small and large intestines. Notably, excessive cellular regeneration appears also a part of the chronic pathogenic process, manifested as activation/proliferation of crypt cells and angiogenesis. The etiology and pathogenic mechanism underlying IBD remain largely elusive. Autoimmunity may play a central role in the pathogenic interplay between genetic predisposition, microbial infection and environmental insults. Serological and other non-gastrointestinal signatures characteristic of autoimmune attack are commonly seen in IBD, especially evident in ulcerative colitis and Crohn’s disease. The mucosa of the GI tract undergoes physiological turnover occurring in every 2–7 days, which may be enhanced under pathological conditions. Polipotent precursors located at the crypts are considered the major reservoir for the normal cellular renewal or pathological regeneration. These local stem cells may proliferate and differentiate into epithelium and glandulous cells in the mucosa. Notably, recent studies suggest that bone marrow mesenchymal stromal cells may participate in GI regeneration especially under pathological conditions, including in IBD. However, less is clear about the differentiation and early integration of BMMSCs in injured intestine. A better understanding of the role of blood-derived stem cells and soluble factors in GI histological and functional repair may shed new light on clinical management of IBD. In the present study we isolated BMMSCs from adult rats, pre-labelled them with a lipophilic red fluorescence dye PKH26.